The vehicle(s) is/are a 1987 Watercraft Sports King Boater Home. The cab consists of a 1986 Ford E-Series, while the rear is a 28-foot power boat that contains living quarters for both land and water use.
There are several like this out on eBay Motors and elsewhere on the web. A quick search for "BoaterHome" will yield plenty of results, though none have been done up quite like this one. With a teardrop window on the cab section and a paint job that would make the Duke Boys blush, this thing is apparently set on celebrating the '70s. That would likely explain the "35" on the side, representing the 35th anniversary of, well...we're not quite sure.
Check out the video below to see how this incredible combo vehicle separates for aquatic use (the action starts at 1:27). The boat may look a little front heavy, but this seems like a best-of-boat both-worlds approach!