The E400 Hybrid comes packed with a 3.0-liter V6 direct-injection engine good for 302 horsepower and 273 pound-feet of torque, supplemented by an electric motor (rated at 27 hp and 207 lb-ft). Official fuel economy ratings haven't been released for the E400 Hybrid just yet, but preliminary data (and the big ol' number on the side of the car) suggests 24 miles per gallon in the city, 32 mpg highway and 27 mpg combined.
Hybrids not your thing? Never fear – Mercedes-Benz will also sell you the less-expensive E350 Bluetec ($52,200, not including destination) that packs a 3.0-liter turbo-diesel V6 good for 210 hp and 410 lb-ft. The 2013 E350 Bluetec hasn't officially been certified by the EPA just yet, but the 2012 model was rated at 21 mpg city and 32 mpg highway (25 combined), and we don't expect those numbers to change.